# Pill for skin disease may also curb excessive drinking, study shows Oregon Health & Science University, 2023. Pill for skin disease may also curb excessive drinking, study shows [WWW Document]. ScienceDaily. URL [https://www.sciencedaily.com/releases/2023/02/230221132118.htm](https://www.sciencedaily.com/releases/2023/02/230221132118.htm) >[!Abstract] > Researchers have identified a pill used to treat a common skin disease as an 'incredibly promising' treatment for alcohol use disorder. On average, people in a proof-of-concept study who received the medication, called apremilast, reduced their alcohol intake by more than half -- from five drinks per day to two. ## Notes - a pill for skin disease may also curb excessive drinking - an estimated 95,000 people in the US die every year from alcohol-related deaths - there are three medications approved for alcohol use disorder in the US %% ## Highlights ### [[a pill for skin disease may also curb excessive drinking]] > Researchers from Oregon Health & Science University and institutions across the country have identified a pill used to treat a common skin disease as an "incredibly promising" treatment for alcohol use disorder. ^g217a > Beginning in 2015, Ozburn and collaborators searched a genetic database looking for compounds likely to counteract the expression of genes known to be linked to heavy alcohol use. Apremilast, an FDA-approved anti-inflammatory medication used to treat psoriasis and psoriatic arthritis, appeared to be a promising candidate. ^53yxp [View Highlight](https://read.readwise.io/read/01gsw25geqxawqva84e9bsf52m) ### [[an estimated 95,000 people in the US die every year from alcohol-related deaths]] > An estimated 95,000 people in the United States die every year from alcohol-related deaths, according to the National Institute on Alcohol Abuse and Alcoholism. ^ya4eo [View Highlight](https://read.readwise.io/read/01gsw26fyn6zqn84kdvd8nnrsa) ### [[there are three medications approved for alcohol use disorder in the US]] > Currently, there are three medications approved for alcohol use disorder in the United States: Antabuse, which produces an acute sensitivity akin to a hangover when alcohol is consumed; acamprosate, a medication thought to stabilize chemical signaling in the brain that is associated with relapse; and naltrexone, a medication that blocks the euphoric effects of both alcohol and opioids. ^ajkv7 [View Highlight](https://read.readwise.io/read/01gsw26j5kpaf77p72za10bcqk)