# What Doctors Don't Know About the Drugs They Prescribe: TedTalk <iframe width="390" height="230" src="https://www.youtube.com/embed/RKmxL8VYy0M" title="YouTube video player" frameborder="0" allow="accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share" allowfullscreen></iframe> [What doctors don't know about the drugs they prescribe | Ben Goldacre - YouTube](https://www.youtube.com/embed/RKmxL8VYy0M) ### Notes The technical term for the phenomenon where unflattering data gets lost, gets unpublished, is left missing in action Reboxetine Anti-depressant 1 study published - shows drug better than placebo 3 studies published - showed drug just as good as any other anti-depressants BUT…7 trials tested drug against placebo 1 +ve = published 6 -ve = left unpublished 3 studies compared drug with other anti-depressant which were +ve and published BUT… 3 x as many showed drug was worse than other drugs and left unpublished! All FDA trials for AntiD 38 +ve results = 37 published 36 -ve results = 3 published