# progesterone production > "Progesterone (P4) is a progestogen produced by the ovary and adrenal glands in the absence of pregnancy and by the corpus luteum and placenta during pregnancy". Progesterone - an overview | ScienceDirect Topics_ (no date). Available at: [https://www.sciencedirect.com/topics/neuroscience/progesterone](https://www.sciencedirect.com/topics/neuroscience/progesterone) - progesterone is produced in small quantities by the adrenal glands? - the majority actually comes after an egg has been released during ovulation - The follicle (the little sac that that the egg was housed in) now becomes a temporary endocrine gland known as the corpus luteum - And it is this corpus luteum that produces the hormone progesterone.